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Dried goji berries may provide protection against age-related macular degeneration

Study shows small serving of the fruit increased protective pigments in the eye

Regularly eating a small serving of dried goji berries may help prevent or delay the development of聽, or AMD, in healthy middle-aged people, according to a small, randomized trial conducted at the University of California, Davis.听

AMD is the leading cause of vision loss in older people and is estimated to affect more than聽聽and 170 million globally.听聽

鈥淎MD affects your central field of vision and can affect your ability to read or recognize faces,鈥 said聽, a co-author of the study and an associate professor in the聽.听

The researchers found that 13 healthy participants aged 45 to 65 who consumed 28 grams (about one ounce, or a handful) of goji berries five times a week for 90 days increased the density of protective pigments in their eyes. In contrast, 14 study participants who consumed a commercial supplement for eye health over the same period did not show an increase.听

Xiang Li

Xiang Li is a doctoral candidate in the UC Davis Nutritional Biology program.

The pigments that increased in the group that ate goji berries, lutein and zeaxanthin, filter out harmful blue light and provide antioxidant protection. Both help to protect the eyes during aging.听

鈥淟utein and zeaxanthin are like sunscreen for your eyes,鈥 said lead author聽, a doctoral candidate in the聽听辫谤辞驳谤补尘.

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鈥淭he higher the lutein and zeaxanthin in your retina, the more protection you have. Our study found that even in normal healthy eyes, these optical pigments can be increased with a small daily serving of goji berries,鈥 said Li.

罢丑别听聽was published in the journal聽.听

Berries used for eye health in China

聽are the fruit of聽Lycium chinense听补苍诲听Lycium barbarum, two species of shrubby bushes found in northwest China. The dried berries are a common ingredient in Chinese soups and are popular as herbal tea. They are similar to raisins and eaten as a snack.

In Chinese medicine, goji berries are said to have 鈥渆ye brightening鈥 qualities. Li grew up in Northern China and became curious whether there were any physiological properties to 鈥渆ye brightening.鈥

鈥淢any types of eye diseases exist, so it is not clear which disease 鈥榚ye brightening鈥 is targeting,鈥 said Li.

She researched the bioactive compounds in goji berries and found they contain high quantities of lutein and zeaxanthin, which are known to聽聽related to AMD. The form of zeaxanthin in goji berries is also a highly bioavailable form, according to Li, meaning it is readily absorbed in the digestive system so the body can use it.

Glenn Yiu

"Our study shows goji berries, which are a natural food source, can improve macular pigments of healthy participants beyond taking high-dose nutritional supplements."

鈥擥lenn Yiu

The current treatment for intermediate stages of AMD uses special dietary supplements, called聽, that contain vitamins C, E, zinc, copper and lutein and zeaxanthin. No known therapy has yet been shown to impact the early stages of AMD.听

The cause of AMD is complex and multifactorial, according to Yiu, and involves a mix of genetic risks, age-associated changes, and environmental factors like smoking, diet and sun exposure. Early stages of AMD do not have symptoms; however, physicians can detect AMD and other eye problems during a regular comprehensive eye exam.听

鈥淥ur study shows goji berries, which are a natural food source, can improve macular pigments of healthy participants beyond taking high-dose nutritional supplements,鈥 said Yiu. 鈥淭he next step for our research will be to examine goji berries in patients with early-stage AMD.鈥澛

Although the results are promising, the researchers note that the study size was small and more research will be needed.

Additional authors on the study include Roberta R. Holt, Carl L. Keen, Lawrence S. Morse and Robert M. Hackman from the University of California, Davis.听

The UC Davis Eye Center


罢丑别听聽provides world-class eye care, pioneers collaborative vision research, and trains the next generation of specialists and investigators to become leaders in the Sacramento region and beyond. The Eye Center team aims to transform vision care and develop cures for blinding eye diseases, from cornea to cortex.